No data were available for oxidised starch (E 1404), monostarch phosphate (E 1410), distarch phosphate (E 1412), hydroxypropyl starch (E 1440), hydroxypropyl distarch phosphate (E 1442), acetylated oxidised starch (E 1451) and starch aluminium octenyl succinate (E 1452). Phosphated distarch phosphate (E 1413) Reproductive toxicity studies: A study was conducted on rats over three generations […]
No data were available for oxidised starch (E 1404), monostarch phosphate (E 1410), distarch phosphate (E 1412), hydroxypropyl starch (E 1440), acetylated oxidised starch (E 1451) and starch aluminium octenyl succinate (E 1452). Phosphated distarch phosphate (E 1413) Rats In an experiment, groups of male and female rats were fed different levels of phosphated distarch […]
The genotoxicity of modified starches was evaluated using an in silico approach due to the lack of available genotoxicity studies. The OECD QSAR Toolbox was used to identify structural alerts for genotoxicity for several modified starches, including distarch phosphate, phosphated distarch phosphate, distarch adipate, acetylated distarch phosphate, acetylated starch, acetylated distarch adipate, hydroxypropyl starch, hydroxypropyl […]
Altered starches, commonly utilized as food additives, play a crucial role in improving the texture, stability, and overall properties of processed foods. Derived from sources such as corn, potato, wheat, or tapioca, these modified starches undergo chemical modifications to enhance their functional attributes. While generally regarded as safe for human consumption, concerns regarding potential health […]
Distarch phosphate was tested for acute toxicity in mice, rats, guinea pigs, rabbits, and cats. The tests showed LD50 values of 7 to 35 g/kg bw, depending on the species, but no deaths occurred. The livers and kidneys of some animals showed no abnormality related to the modified starch. The available data suggests that the […]
Some dietary polysaccharides like starches can be partially broken down by enzymes like amylase in the human digestive tract. This results in intermediate metabolites like lactic, acrylic, or fumaric acid, which are further broken down by bacteria in the colon to produce short-chain fatty acids (SCFA) such as acetic, propionic, and butyric acids. These SCFAs […]